• 1999.09—2004.06  新乡医杏鑫临床医学专业本科生

• 2004.09—2009.06  杏鑫娱乐上海医杏鑫中西医结合基础专业博士研究生

• 2009.07—2015.11  杏鑫讲师

• 2013.11—2014.11  美国哈佛大学附属麻省总医院麻醉科博士后

• 2015.12—至今     杏鑫副教授

• 2016☝🏼，尚学计划🥷🏿，杏鑫

• 2015⛽️，卓学计划，杏鑫娱乐

• 2009，研究学者，杏鑫娱乐上海医杏鑫

• 2018，杏鑫娱乐2018年度青年教师教学竞赛（医科组）三等奖

• 2016，杏鑫娱乐第一三共奖教金

• 2016🕡，中国中西医结合学会科学技术二等奖（第三完成人）

• 2015🧯，中国神经科学会赛诺菲优秀会议论文奖

• 疼痛及中药、针刺、运动镇痛的神经生物学机制

• 瘙痒及中药、针刺止痒的神经生物学机制

• 2023,国家自然科学基金面上项目，IL-33调控vlPAG星形胶质细胞-GABA能神经元互作介导神经病理性冷痛的作用及机制♐️，主持

• 2022，科技创新2030—脑科学与类脑研究重大项目，胶质细胞在中枢神经系统稳态和功能维持中的作用，项目骨干

• 2021，上海市教委高水平地方高校试点建设重点创新团队，针刺治病的神经-内分泌-免疫网络机制🧘🏽‍♀️，参与

• 2019，上海市教委高水平地方高校试点建设战略创新团队, 针灸神经免疫网络及调控机理,参与

• 2018，国家自然科学基金面上项目，冷受体TRPM8在IL-33介导神经病理性冷痛中的作用及机制，主持

• 2017，上海市卫生和计划生育委员会科研课题青年项目🦵🏿，脊髓NALP1炎症小体在姜黄素缓解小鼠神经痛中的作用及机制🧙🏿‍♂️，主持

• 2015，上海市自然科学基金，脊髓IL-33/ST2通路在慢性吗啡镇痛耐受中的作用及信号机制，主持

• 2011，国家自然科学基金青年项目🧑‍🎓，脊髓IL-33/ST2通路在大鼠关节炎痛中的作用及细胞分子机制🗳🌥，主持

• 2011，教育部博士点基金新教师基金项目，脊髓IL-33/ST2通路在电针缓解大鼠关节炎痛中的作用及细胞分子机制，主持

本科生课程：

• 中西医结合基础概论♖、疼痛生物医学、走近医学👙：历史与传承、疼痛：隐藏的慢性杀手、医学生综合素养🎾、中西医学大师与人文素养

研究生课程：

• 医学研究生学习导引♓️、神经科学原理、中西医结合基础概论👯、疼痛生物医学☝🏼、疼痛研究技术与方法、慢性疼痛

• 2023-今 上海医学会疼痛学专科分会青年委员会副主任委员

• 2023-今 中国针灸学会针刺麻醉分会委员

• 2020-今 中国神经科学学会胶质细胞委员会委员

• 2020-今 中国中西医结合学会科研院所工作委员会委员

1. Chenghao Wang¹, Hui He¹, Tianchi Gao, Xinzheng Sun, Lixia Du, Yayue Yang, Jianyu Zhu, Yachen Yang, Yanqing Wang, Wenli Mi*. Analgesic Effect of Exercise on Neuropathic Pain via Regulating the Complement Component 3 of Reactive Astrocytes. Anesthesia & Analgesia. 2024 Jan 31.

2. Yayue Yang¹, Lixia Du¹, Jianyu Zhu, Ting Yi, Yachen Yang, Zheng Qiao, Qiliang Maoying, Yuxia Chu, Yanqing Wang, Wenli Mi*. Antipruritic effects of geraniol on acute and chronic itch via modulating spinal GABA/GRPR signaling. Phytomedicine. 2023, 119:154969.

3. Xinyi Gao¹, Yayue Yang¹, Jianyu Zhu, Yuxin Zhang, Chenghao Wang, Zhifei Wang*, Wenli Mi*, Lixia Du*. Xanthotoxol relieves itch in mice via suppressing spinal GRP/GRPR signaling. European Journal of Pharmacology. 2023, 960:176147.

4. Ling Xu¹, Ming-Zhe Liu¹, Ya-Yue Yang¹, Yan Wang, Xiao-Xiao Hua, Li-Xia Du, Jian-Yu Zhu, Yang Shen, Yan-Qing Wang, Ling Zhang, Wen-Li Mi*, Di Mu*. Geraniol enhances inhibitory inputs to the paraventricular thalamic nucleus and induces sedation in mice, Phytomedicine, 2022, 153965.

5. Xue-Ming Hu¹, Wei Yang¹, Meng-Ting Zhang¹, Li-Xia Du, Jia-He Tian, Jian-Yu Zhu, Yu Chen, Feng Hai, Shen-Bin Liu, Qi-Liang Mao-Ying, Yu-Xia Chu, Hong Zhou, Yan-Qing Wang, Wen-Li Mi*. Glial IL-33 signaling through an ST2-to-CXCL12 pathway in the spinal cord contributes to morphine-induced hyperalgesia and tolerance, Science signaling, 2021, 14(699): eabe3773.

6. Lixia Du, Xueming Hu, Wei Yang, Hanikezi Yasheng, Shenbin Liu, Wenwen Zhang, Yang Zhou, Wenqiang Cui, Jianyu Zhu, Zheng Qiao, Qiliang Maoying, Yuxia Chu, Hong Zhou, Yanqing Wang, Wenli Mi*. Spinal IL-33/ST2 signaling mediates chronic itch in mice through the astrocytic JAK2-STAT3 cascade. Glia. 2019 67(9):1680-1693.

7. Lixia Du, Yanqing Wang, Guoqiang Hua, Wenli Mi*. IL-33/ST2 Pathway as a Rational Therapeutic Target for CNS Diseases. Neuroscience 2018 369: 222–230.

8. Wenli Mi, Shuxing Wang, Zerong You, Grewo Lim, Michael F. McCabe, Hyangin Kim, Lucy Chen, Jianren Mao*. Nortriptyline Enhances Morphine-Conditioned Place Preference in Neuropathic Rats: Role of the Central Noradrenergic System. Anesthesia & Analgesia. 2017 125(3):1032-1041.

9. Shenbin Liu1, Qian Li1, Mengting Zhang, Qiliang Maoying, Langyue Hu, Gencheng Wu, Wen-Li Mi*, Yanqing Wang*. Curcumin ameliorates neuropathic pain by down-regulating spinal IL-1β via suppressing astroglial NALP1 inflammasome and JAK2-STAT3 signalling. Scientific Reports. 2016;6:28956.

10. Shenbin Liu1, Wenli Mi¹, Qian Li, Mengting Zhang, Ping Han, Shan Hu, Qiliang Maoying, Yanqing Wang*. Spinal IL-33/ST2 signaling contributes to neuropathic pain via neuronal CaMKII-CREB and astroglial JAK2-STAT3 cascades in mice. Anesthesiology, 2015 123(5):1154-1169.

11. Ping Han¹, Shenbin Liu¹, Mengting Zhang¹, Jing Zhao, Yanqing Wang, Gencheng Wu, Wenli Mi*. Inhibition of spinal Interlukin-33/ST2 signaling and downstream ERK and JNK pathways in electroacupuncture analgesia in formalin mice. PLOS ONE, 0129576, 12, 2015.

12. Ping Han, Jing Zhao, Shen-Bin Liu, Chang-Jiang Yang, Yan-Qing Wang, Gen-Cheng Wu, Da-Mo Xu, Wen-Li Mi*. Interleukin-33 mediates formalin-induced inflammatory pain in mice. Neuroscience, 2013 241:59-66.

13. Wen-Li Mi, Qi-Liang Mao-Ying, Xiao-Wei Wang, Xiu Li, Chang-Jiang Yang, Jian-Wei Jiang, Jin Yu, Jun Wang, Qiong Liu, Yan-Qing Wang*, Gen-Cheng Wu. Involvement of spinal neurotrophin-3 in the electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis. Journal of Pain. 2011 12(9):974-84.

1. 一种简易型电动抚触装置 (已授权：ZL202223574272.1)

2. 一种慢性瘙痒动物模型的制备器 (已授权：ZL201820822114.8）

3. 抗ST2/IL-1 R4抗体在制备镇痛药物中的用途 (已授权：ZL201210517242.9）

4. 抗ST2/IL-1 R4抗体在制备防治瘙痒药物中的应用 (已授权：ZL201210517244.8）