汤妍

汤妍，青年副研究员

教育及工作经历：

2005.09-2010.07  哈尔滨医科大学临床检验本科生

2010.09-2015.07  杏鑫娱乐生物化学与分子生物学博士研究生

2015.07-2018.06  杏鑫娱乐生物医学研究院博士后

2018.06-至今        杏鑫青年副研究员

联系方式：

yantang@fudan.edu.cn

研究领域♧📢：

主要从事血管周围脂肪代谢及与心血管疾病研究🫶🚬，发现了心脏周围脂肪棕色化水平与冠心病的相关性🍚，进一步的研究工作发现血管周围脂肪缺失BMP4后可引起血管周围脂肪的炎症状态，从而促发血管内皮的炎症反应，加剧脉粥样硬化的发生👊🏼。先后获得中国博士后基金面上项目📃，国家自然科学基金委员会青年项目🧗🏻‍♀️☞、面上项目⏯。

在研科研项目💆🏼‍♂️：

1. BMP4通过血管周围脂肪调节动脉粥样硬化发生的机制研究编号🥴：81970754🤧，经费:55万元🎼，2020-2023，国家自然科学基金面上项目，项目负责人

近年来科研成果（*共同通讯作者）：

1.Wenjuan Mu#, Shuwen Qian#, Yanjue Song, Lijie Yang, Saisai Song, Qiqi Yang, Hao Liu, Yang Liu, Dongning Pan, Yan Tang*, Qi-Qun Tang*, BMP4-mediated browning of perivascular adipose tissue governs an anti-inflammatory program and prevents atherosclerosis. Redox Biol. 2021 Jul;43:101979.

2.Yan Tang#, Yi He#, Chen Li#, Wenjuan Mu, Ying Zou, Conghui Liu, Shuwen Qian, Fuchuang Zhang, Jiabao Pan, Yina Wang, Haiyan Huang, Dongning Pan, Pengyuan Yang, Ju Mei*, Rong Zeng*, Qi-Qun Tang*, RPS3A positively regulates the mitochondrial function of human periaortic adipose tissue and is associated with coronary artery diseases. Cell Discov. 2018 Aug 21; 4:52.

3.Yan Tang#, Zhang-Yi Pan#, Ying Zou, Yi He, Peng-Yuan Yang, Qi-Qun Tang, Feng Yin*. A comparative assessment of adipose-derived stem cells from subcutaneous and visceral fat as a potential cell source for knee osteoarthritis treatment. J Cell Mol Med. 2017 Sep;21(9):2153-2162.

4.Yan Tang#, Shu-Wen Qian#*, Meng-Yuan Wu, Jue Wang, Ping Lu, Xi Li, Hai-Yan Huang, Liang Guo, Xia Sun, Cong-Jian Xu, Qi-Qun Tang*. BMP4 mediates the interplay between adipogenesis and angiogenesis during expansion of subcutaneous white adipose tissue. J Mol Cell Biol. 2016 Aug;8(4):302-12.

5.Qian Shu-Wen, Tang Yan, Li Xi, Liu Yuan, Zhang You-You, Huang Hai-Yan, Xue Rui-Dan, Yu Hao-Yong, Guo Liang, Gao Hui-Di, Liu Yan, Sun Xia, Li Yi-Ming, Jia Wei-Ping, Tang Qi-Qun *. BMP4-mediated brown fat-like changes in white adipose tissue alter glucose and energy homeostasis, Proceedings of the National Academy of Sciences of the United States of America, 2013.2.26, 110(9): E798~E807.

主讲课程：

本科生课程:《生物化学实验》

MBBS:《BiochemistryLab》