杏鑫娱乐特聘教授👣、博士生导师🏃🏻♀️➡️，国家杰出青年科学基金获得者、上海市领军人才、上海市优秀学科带头人，国务院特殊津贴专家🧚🏿。1992、1997年二次获笹川医学奖学金赴日本留学；1999年获博士学位。1999年起任日本学术振兴会JSPS博士后、大阪生命科学研究所研究员，研究副部长；2005年12月加盟杏鑫娱乐。现任杏鑫娱乐开户药理学系主任。
Mesencephalic dopaminergic neurons are essential for modafinil-induced arousal.Br J Pharmacol. 2021 Aug 16. doi: 10.1111/bph.15660. Online ahead of print.
Wang YQ, Liu WY, Li L, Qu WM, Huang ZL*. Neural circuitry underlying REM sleep: A review of the literature and current concepts. Progress in Neurobiology. 2021 Jun 15:102106. doi: 10.1016/j.pneurobio.2021.102106.
Shen Y, Yu WB, Shen B, Dong H, Zhao J, Fan Y, Yang YF, Sun YM, Luo SS, Chen C, Liu FT, Tang YL, Wu JJ, Xiao BG, Yu H, Koprich JB, Huang ZL*, Wang J*. propagated alpha-synucleinopathy recapitulates RBD followed by Parkinsonian phenotypes in mice. Brain, 2020, 143; 3374–3392.
Zhang Z, Liu WY, Diao YP, Xu W, Zhong YH, Zhang JY, Lazarus M, Liu YY, Qu WM*, and Huang ZL*. Superior colliculus GABAergic neurons are essential for acute dark-induction of wakefulness in mice. Current Biology, 2019 Feb 18; 29(4):637-644.
Luo YJ, Li YD, Wang L, Yang SR, Yuan XS, Wang J, Cherasse Y, Lazarus M, Chen JF, Qu WM*, and Huang ZL*. Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors.Nature Communications, 2018 Apr 20;9(1):1576. doi: 10.1038/s41467-018-03889-3.
Wu YE, Enoki R*, Oda Y, Huang ZL*, Honma K, Honma S. Ultradian Calcium Rhythms in the Paraventricular Nucleus and Subparaventricular Zone in the Hypothalamus. Proc Natl Acad Sci U S A. 2018; 115(40):E9469-E9478.
Yang SR*, Hu ZZ, Luo YJ, Zhao YN, Sun HX, Yin D, Wang CY, Yan YD, Wang DY, Yuan XS, Ye CB, Guo W, Qu WM, Cherasse Y, Lazarus M, Ding YQ, Huang ZL*. The rostromedial tegmental nucleus is essential for non-rapid eye movement sleep. PLoS Biology, 2018 Apr 13;16(4):e2002909. doi: 10.1371/journal.pbio.2002909.
Yuan XS, Wang L, Dong H, Qu WM, Yang SY, Cherasse Y, Lazarus M, Schifmann S, de Kerchove d'Exaerde A, Li RX* and Huang ZL*. Striatal adenosine A2A receptor neurons control active-period sleep via parvalbumin neurons in external globus pallidus. eLife, 2017 Oct 12;6. pii: e29055. doi: 10.7554/eLife.29055.
Oishi Y, Xu Q, Wang L, Zhang BJ, Takahashi K, Takata Y, Luo YJ, Cherasse Y, Schifmann S, de Kerchove d'Exaerde A, Urade Y, Qu WM, Huang ZL* and Lazarus M*. Slow-wave sleep is controlled by a subset of nucleus accumbens core neurons in mice. Nature Communications, 2017 Sep 29;8(1):734. doi: 10.1038/s41467-017-00781-4.
Zhang Z, Wang HJ, Wang DR, Qu WM* and Huang ZL*.Red light at intensities above 10 lx alters sleep-wake behavior in mice. Light: Science & Application, 2017 May 6; e16231; doi:10.1038/lsa.2016.231
Oishi Y, Huang ZL*,Fredholmd BB, Uradea Y and Hayaishi O*. Adenosine in the tuberomammillary nucleus inhibitsthe histaminergic system via A1 receptors andpromotes non-rapid eye movement sleep. Proc Natl Acad Sci USA, 2008, 105(50):19992-19997.
Qu WM, Huang ZL*, Xu XH, Matsumoto N and Urade Y. Dopaminergic D1 and D2 receptors are essential for the arousal effect of modafinil. J Neurosci 2008, 28(34): 8462-8469.
Huang ZL, Mochizuki T, Qu WM, Hong ZY, Watanabe T, Urade Y and Hayaishi O. Altered sleep-wake characteristics and lack of arousal response to H3 receptor antagonist in histamine H1 receptor knockout mice. Proc Natl Acad Sci USA 2006, 103(12): 4687-4692.
Qu WM, Huang ZL, Xu XH, Aritake K, Eguchi O, Nambu F, Narumiya S, Urade Y and Hayaishi O. Lipocalin-type prostaglandin D synthase produces prostaglandin D2 involved in regulation of physiological sleep. Proc Natl Acad Sci USA, 2006; 103(47):17949-17954.
Huang ZL, Qu WM, Eguchi, N, Chen JF, Schwarzschild MA, Fredholm BB, Urade Y and Hayaishi O. Adenosine A2A, but not A1, receptors mediate the arousal effect of caffeine. Nat Neurosci 2005; 8(7): 858-859.
Huang ZL, QuWM, LiWD, MochizukiM, EguchiN, WatanabeT, UradeY and HayaishiO. Arousal effect of orexin A depends on activation of the histaminergic system. Proc Natl Acad Sci USA2001; 98(17):9965-9970.